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2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid

Development stage: Preclinical
Lead developer: AstraZeneca
Modality: Small Molecules

Overview

This compound is a small molecule identified as a GPR40 (FFAR1) agonist. It was developed by AstraZeneca and is described in patent WO2015107400A1 for the potential treatment of type 2 diabetes. GPR40 agonists aim to improve glycemic control by stimulating glucose-dependent insulin secretion.

Targets

FFAR1 (Free fatty acid receptor 1)

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